Target Region Methylation Capture

︱Product Description    ----------------------------------------------------------------------------------------------------------

Target Region Methylation Capture Sequencing utilizes custom-designed probes targeting specific genomic regions of interest. These probes hybridize with genomic DNA to capture and enrich target sequences, which then undergo bisulfite conversion followed by high-throughput sequencing. Our company offers two distinct target region methylation capture technologies that seamlessly integrate targeted capture with methylation detection. This approach enables high-throughput, high-precision methylation analysis of specific genomic regions of interest, providing a comprehensive, stable, efficient, and cost-effective methodology for methylome studies to meet diverse research requirements.

︱Key Advantages    ---------------------------------------------------------------------------------------------------------------

● High Precision

   Achieves single-base resolution for comprehensive coverage of all methylation sites within targeted genomic regions and related genes.

● Protocol Flexibility

   Two optimized technical solutions for different research needs: low-input (BisCap) and standard-input (MethCap) protocols.

● Dual Applications

Single panel design supports both mutation detection and methylation analysis (MethCap)

● Low Input Requirements

   Suitable for limited samples including cell-free DNA (BisCap).

● Custom Design

   Personalized targeting for any genomic region of interest.

● Cost-Effective

   Direct capture of target regions significantly reduces sequencing costs.